Call variants from a path discovered from the reads
Call variants from a path discovered from the reads
Possible paths through the reads
Start locus on the reference contig or chromosome
Reference sequence overlapping the reference region
Function that returns a ReadAlignment from the path
Function to build a called variant from the (Locus, ReferenceAllele, Alternate)
If true, output variants where the reference and alternate are the same
Possible sequence of called variants
Window of reads that overlaps the current loci
Length kmers in the DeBruijn graph
Minimum times a kmer must appear to be in the DeBruijn graph
Expected ploidy, or expected number of valid paths through the graph
Number of paths to align to the reference to score them
Collection of paths through the reads
Heuristic to determine when a region has a complex collection of region alignments This is based on reads with multiple mismatches or insertion / deletion alignments
Heuristic to determine when a region has a complex collection of region alignments This is based on reads with multiple mismatches or insertion / deletion alignments
Set of reads in a reference region
Reference contig for the region
Minimum fraction of reads needed
True if the 'active' region